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I’ve never felt so sick as today. I’ll try to look into a positive side and think this as an opportunity to think back at my past behaviors.
Well, it’s okay to feel bad.. I’ve been working all day, exploring things that I couldn’t do as a student back in high school. It’s okay to let go this evening. Stay calm.. it’s okay.. Everything will be okay. You’ll do just fine. You can wake up early tomorrow to resume the research.
Organic chemistry. Data Science. Python. Biostatistics. Gravity energy storage. GTP-1. Cellular Agriculture’s market potentials and business models. Using metabus to increase students’ engagements in learning?Would AI be introduced as a tool when I get to pharmacy college next year? International interventions to address ongoing Cameroon separatists’ attacks. Could sodium sulfur battery be good alternative to lithium battery? What are some drawbacks when using scorpion venom as a cancer treatment? Public perceptions? Who should be the next president for S. Korea? Should I support Lee Jae myung from Democratic Party? How to use plexin A4 protein to reduce amyloid in Alzheimer’s patient? Why aren’t seeing this being used in a clinical settings? protein Why did interferon beta 1-a increase inflammatory responses towards COVID-19 patients requiring mechanical ventilations. What if we didn’t prescribe with antiviral remedesivir?Then, would the result change as interferon beta 1-a is known to inhibit viral replication though it doesn’t target same enzymeScientific mechanism behind mensturation bleeding post vaccination. Nuclear and Missile diplomacy between the US and North Korea. Why do heart inflammation occur following Pfizer vaccination for a few men? History of sex segregated bathrooms. Understanding S. Korean Economic Development to apply to developing economies.
Improving policies towards Afghan refugees in Korea. Recruiting volunteers. Cooking breakfast and dinner for my sister. Learning mathematics in Korean to tutor my sister.
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636 kcal
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Rasva: 21,72g | Prot: 50,96g | Hh: 58,40g.
Aamiainen: Apples . Lounas: Plain Yogurt, Roasted Chestnuts, Boiled Egg, Chicken Breast. lisää...
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 Kommentit
Clogged by so many thoughts!! I can’t wait to work tomorrow!!! I’m sick but am full of questions to investigate
26 loka 21 jäseneltä: HGemmac
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CRISPR-Cas13d system developed by Stanford could be a good alternative to remedisivir as it inhibits the expression of genes that encode for RdRp which is the target of remedisivir but would liposome delivery system or other delivery systems be good? Why aren’t we seeing progress in a clinical setting?? How can I support?
26 loka 21 jäseneltä: HGemmac
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I’m recording things that are instantly coming up in my mind so I could refer back tomorrow.. just ignore upcoming comments.. 😢
26 loka 21 jäseneltä: HGemmac
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Wow, so many questions. People often take years and years and may not be able to answer these questions. Let your mind rest and call it a night. There is a fine balance between mind and body. I am seeing more and more younger generation who are constantly keeping their mind churning. It's all good, I wish my mind was that active when I was your age. Just pace yourself, I know it's tough to slowdown and smell the flowers. Now I am older, looking back to those days, I wish I slowdown a bit. We sure can't take back the time. What you're doing with your sister is awesome. She will remember.
26 loka 21 jäseneltä: Tai_1-9
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Thank you, I always appreciate your time and sharing your life long advice. This one in particular reminds me of Herbert Hoover’s quote: “Be patient and calm; no one can catch a fish in anger”. it’s really a time for me to sleep 😴 I was keep contemplating the potential causes behind my stomach issues and I realized my symptoms are fairly similar to keto flu. Pretty scary yet insightful to know. Have a nice day Tai👍 Stay safe and healthy too! 🤛
26 loka 21 jäseneltä: HGemmac
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Haha. I can relate to this so much! Brain, high on information. I agree with Tai. Also, it gets better with age. What helps me now - is knowing (and believing) that there are people out there who are working and thinking on some of these topics. You don't have to do all the thinking on your own.😂
I'll contribute my two cents on the above topics:
CRISPR-Cas systems are far away from being used in general population. They can be used to do a lot of hard core gene editing, but for now the in vivo use is reserved for rare and untreatable diseases, since severe side effects are not an issue if you are facing certain death. I don't see Cas proteins being used for regular di?treatment any time soon. Gene therapy is my specialty, so I can say it with some confidence. Liposomal delivery (less popular) and AAV delivery are both quite possible
Plexin-A4 downregulation, hypothetically speaking, should prevent toxic accumulation of tau. However, by the time the symptoms present in Alzheimer's patients, the tau aggregates are already fully formed. With Plexin-A4 downregulation you might prevent further accumulation of tau, but for most patients - that's not enough since most of neuronal damage has been already done. Preventative treatment with something like that would be ideal, but since Alzheimer's disease doesn't have direct genetic causes - it is not justifiable to use preventative treatment on people who might or might not develop the symptoms.
Maybe someone can add info on your other questions. Pool some brains together rather than overload your own.
28 loka 21 jäseneltä: EyesoftheBlueDog
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Thank you!!! I was referring to two CRISPR systems which inhibit the expression of Spike and Nucleocapsid proteins: CRISPR-Cas13b System developed by researchers in Melbourne, Australia, and CRISPR-Cas13d developed by researchers at Stanford Bioengineering Department. Former had a >98% silencing efficiency w/ their ability to target the strains that evade neutralizing antibodies & latter targeted 91% of sequenced SARS-CoV-2. I found these results so captivating and wondered why these are not being used in clinical settings haha. Ohh!! Didn’t know that! I only thought about delivering within nanopolymers, liposomes, or through ribonucleoprotein complex. Well, I’m going to research delivery using viral vector too. Yea, I agree with what you said about plexin A4. I haven’t seen drugs that prevent Alzheimer’s though aducanumab’s mechanism of action seems to suggest it does so by clearing beta amyloid but clinical trials only involved those with mild cognitive symptoms & the costs are astronomically high (who could afford $56,000 for the drug that’s so controversial in public ?!)!
28 loka 21 jäseneltä: HGemmac
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I was thinking these questions by myself, surfing pubmed, (sometimes biorxiv & research gate), nature, and NEJM. It’s difficult to find or collaborate with experts as I’m not currently a student and my resources and depth of knowledge are limited. I just became fascinated about genetics, biotech, and molecular bio by taking courses in coursera and doing some independent research 😅 I’m sure I made very naive judgments and my info are wrong in some ways!! Thank you for your response!! I recorded your contributions in my excel file which compiles all the questions I’m curious about & answers with sources. Thanks again! Love collaborating 👍❤️
28 loka 21 jäseneltä: HGemmac
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You comments are extremely well thought through; not naive at all. I went to grad school for seven years to be able to comment on something like that. You've picked it up through Coursera courses and reading Pubmed. That's truly amazing and very impressive. It takes people years to learn to read scientific articles, never mind mine through them and make educated predictions. My comments were something I got to know from being in biotech industry - it's not something that someone can know from reading literature. To pick up information like that - you'd need to talk to someone in the field. One of the ways you can achieve that without being involved in the field - is by attending biotech/pharma career events. These are usually used for job search/networking. However, there are no requirements at all to attend. I've found that those events are ideal to pick peoples brains on any topic you want. People are very happy to talk about their jobs and what they do. Don't know whether it's easy to get into those in Korea, but there are plenty in the US online that you can attend. They usually happen around 5-6 pm eastern US time - which is roughly 6-7AM Seoul time.
28 loka 21 jäseneltä: EyesoftheBlueDog
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Ha! Sorry. I just realized that I'm probably adding more tasks on your plate and increasing your anxiety. That is definitely not the point. Take it easy. You are doing A LOT already and doing it well! Cudos to you.
28 loka 21 jäseneltä: EyesoftheBlueDog
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Thank you!! No, you didn’t!! It’s extremely helpful to hear someone in the field and I’m so grateful to get some answers for my future paths! I found some pretty interesting biotech webinars in eventbrite and registered for three that’s on November! There are very few in Korea and often it’s reserved for those working in the fields 😂 I’d probably keep attending events in the US and making new connections and building professional networks! Thanks a lot!
28 loka 21 jäseneltä: HGemmac
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